CAFE - Common Application Framework Extensible

CAFE Projects

CAFÉ was initially developed for Clinical Trial Mangement. It has now been generalized for use with all manner of applications, such as epidemiologic studies, prevention trials, laboratory management, tissue repositories, tissue microarray data capture, and administrative systems.

Types of information we can gather: questionnaire/surveys, patient/subject demographics, clinic visit forms, clinical exam forms, lab results, microarray/genomic data, specimen collection, and contact tracking of study participants.

Dozens of PIs from across the entire Health Science campus, as well as from some Cancer Centers across the country, are our customers.


Example projects:

Adult CTMS System for Norris Cancer Center

Clinical Trials Management system for Norris Cancer Center Trials. The allows for the collection of all protocol and patient related data. This is an integrated system that allows for easy data entry and reporting. This is our flagship application with over 500 different forms, over 1000 reports and over 200 users.

Cancer Center Membership, Publications & Grant Management

This application has been created for the USC Norris Cancer Center administration office. The application helps manage the information for all Cancer Center Members, their grants, publications, and biosketches. It automatically downloads publications from PubMed, and members easily approve and categorize their publications. All NCI reports are integrated in the application. Currently 4 institutions use this tool.

See Detailed Description

Young Women's Health History Study

This is a breast cancer case-control study which compares the health, lifestyles, and genetic factors of young women with breast cancer to controls, in an effort to identify risk factors for breast cancer. It includes subjects from 2 locations and investigators from 5 different institutions, such as the University of Wisconsin, Michigan State University, and USC. Cafe provides complex data collection forms, reports and dashboards to manage the entire study, making it far easier, faster and less expensive to than other options.

NANT Consortium Pediatric CTMS System

This application was created for pediatric studies for NANT (New Approaches to Neuroblastoma Therapy). This application includes modules for Protocol Data, Patient Demographics, Specimen Tracking, Treatment Roadmap, Toxicities, Evaluation of Response, End of Course etc...

USC Comprehensive Epilepsy Center

The application centralizes data recordings for USC Comprehensive Epilepsy Center, aiding data collection on initial neuropsychology (multi-lingual), quality of life, Phase One data, surgical parameters and seizure history. It also supports conference planning for scientifically reviewing subjects with reports adhering to ILAE classifications.

Cancer Concerns
Cal. State Cancer Concerns Management

This application has been adopted by the State to enter the information for all Cancer Concerns raised by the residents of California. This application allows the Cancer Registries from all California regions to not only enter the inquiries but also allows them to track the number of hours they spent working on each inquiry. The application included numerous on demand reports summarizing the information entered in the system.

Los Angeles Cancer Surveillance Program
Los Angeles Cancer Surveillance Program – Document Management

This application allows the CSP to manage secure communication and transfer of files between the CSP and all local hospitals.  This application has saved CSP thousands of dollars in shipping and reduced delays and added efficiency.

Cystic Fibrosis
USC Cystic Fibrosis In-Clinics Patient Management

This application has been custom created for Cystic Fibrosis Clinic to capture the patient information for all their patients. This is a stripped down version of a Electronic Medical Record System that allows the Clinic to operate efficiently by reducing duplication of efforts and a reduction of paper documents.

Health Journalism Fellowship Management

This application is being used by USC’s Annenberg School of Communication to capture information on all fellowships conducted by the School. A website accepts applications for the fellowships online and the school uses it to manage all aspects of the fellowships including assigning applicants to fellowships, vendors, payments, attendance, etc...




"I find CAFE overall the best compared to other databases I have used."
- Judy Villablanca, Associate Professor Clinical Pediatrics, Childrens Hospital Los Angeles, Medical Director, NANT

"I now always plan to incorporate the very reasonable costs of development of a CAFÉ database in my new grant submissions."
- Ann S. Hamilton, Ph.D.

"I can't speak highly enough of the skill and helpfulness of the Informatics Team at USC Norris. ...Informatics developed a customized version of CAFÉ that has proved to be a perfect fit for us in seminar event planning, tracking of program participants and more."
- Michelle Levander, Director, The California Endowment Health Journalism Fellowships

"Three years ago, the KSOM Research Advancement Office approached the Cancer Center Informatics Research Core (CRIC) about developing a grant awards and space occupation database for us to manage our $200M plus grant portfolio and KSOM’s 960,622 net square feet of space. (CRIC) worked closely with us to create a comprehensive database that is user friendly and invaluable in our day to day operations."
- Linda Mizushima, USC KSOM
- Janet A. Stoeckert, USC KSOM

"...Adding fields to café for capturing other unique information needed for reports can generally be done by CRIC quickly and efficiently."
- Kay Johnson

"I have found that just about any (CAFE) configuration is possible...(and) my staff members have found the databases easy to use."
- Ann S. Hamilton, Ph.D.

"The team has done a fabulous job developing the data management system and has been extremely responsive to any “tweaking” needed. As we submit our U01, I will definitely continue to use CAFÉ... It has far exceeded my expectations."
- Sharon A. Cermak
Professor of Occupational Science and Occupational Therapy
University of Southern California