CAFE - Common Application Framework Extensible

Testimonials


"I have found the CAFÉ staff to be very helpful and responsive to the different needs of each study. They have the ability to produce databases and summary reports tailored to my specifications, and I have found that just about any configuration is possible. Multiple files can be linked together. With experience they have gained from providing databases for previous studies there are many examples to look at to get ideas for a new study. My staff members have found the databases easy to use, and when multiple staff members are working on a study, the latest updates can be viewed by all. In addition to tracking databases I have also had online questionnaires developed. Information is kept secure and backed up, thus assuring that confidential data are protected and minimizing the concern about losing information. I now always plan to incorporate the very reasonable costs of development of a CAFÉ database in my new grant submissions."

Ann S. Hamilton, Ph.D.
Associate Professor
Keck School of Medicine, University of Southern California
USC/Norris Comprehensive Cancer Center
1441 Eastlake Ave, Rm 3427A, MC9175
Los Angeles, CA 90089-9175
323-865-0434
ahamilt@usc.edu

Three years ago, the KSOM Research Advancement Office approached the Cancer Center Informatics Research Core (Informatics) about developing a grant awards and space occupation database for us to manage our $200M plus grant portfolio and KSOM’s 960,622 net square feet of space. (CRIC) worked closely with us to create a comprehensive database that is user friendly and invaluable in our day to day operations. Aarti’s team continues to provide database development support by building reports and adding data fields as needed. For example, we have since added post-doc information to the database to meet our NSF post-doc reporting requirements.


Linda Mizushima, Director of Research Facilities, USC KSOM
Janet A. Stoeckert, Director, Research Administration, USC KSOM

"I can't speak highly enough of the skill and helpfulness of the Informatics Team at USC Norris. Informatics developed a customized version of CAFÉ that has proved to be a perfect fit for us in seminar event planning, tracking of program participants and more."

Michelle Levander, Director
The California Endowment Health Journalism Fellowships
USC Annenberg School of Journalism

"We have utilized the CAFE database for our Phase I/II trials in the New Approaches to Neuroblastoma Therapy (NANT) consortium. I am the Medical Director of our NANT Operations Center and have helped design our CAFE database and I use it extensively. These trials are performed at 16 sites in the US/Canada and are detailed/complex novel agent trials which require complex data of high quality. We enter 45-50 patients per year on trials. I have also run studies that have utilized Medidata and the COG database (RDE 1 and 2) as a comparison to CAFE.

The CAFE system has been a great asset to our trials, especially for the following reasons:

  • 1. We have set up individual databases for each unique clinical protocol, but we also have a demographic/followup database which is linked to the individual ones, to allow us to do analyses for all patients entered on any NANT study. This type of cross-talk is not available in the commercial databases I have used to date.
  • 2. We have set up standard reports that update automatically as new data is entered into each datafield that allow rapid and up to the minute summary tables to be accessed for use on study status, examining a DLT In context of all study toxicity, etc. This feature is not available on other databases I have used. THis is one of best features of CAFE.
  • 3. The web access allows our study chairs to have read only access to their study data and the summary tables, which facilitates their oversight of study conduct. I am easily able to access CAFE to prepare reports as needed.
  • 4. We utilize a set of generic forms across studies, but are able to design study specific forms very easily that access the data as we need it; instead of being forced into a set format as many commercial databases require. Our toxicity form includes a "lookup' of CTC toxicity definitions which makes toxicity entry very easy.
  • 5. CAFE is very user friendly, it is easy to change patient being viewed, view different forms, and the forms themselves are easy to read on one page instead of requiring scrolling so the top/bottom are not visibile at once. We have had very positive comments from our NANT Study chairs.
  • 6. The review/lock feature allows us to know what data has been reviewed , what queries made, and the responses.
  • 7. CAFE will allow us to use remote data entry, this is in place successfully at one of our sites.

I find CAFE overall the best compared to other databases I have used."

Judy Villablanca
Associate Professor Clinical Pediatrics
Childrens Hospital Los Angeles
Medical Director, NANT

"As an investigator with many studies, Cafe allows me to develop the data management infrastructure I need, benefiting from similar work on many previous studies. The support staff provide a much broader skill set than I could provide on each individual study."

Dennis Deapen, DrP.H.
Director
USC Cancer Surveillance Program

"As the Associate Director for the Clinical Investigations Support Office, USC’s Clinical Trials Office, I use café multiple times daily, looking at data that resides on Café Protocol and Café Patients. We capture in Café all information needed for generating reports to the NCI. There are ‘canned’ reports set up for me that have been developed over the years based on either required NCI reports, reports needed for Grants or requests from PIs for specific types of information. Because café was developed at USC, adding fields to café for capturing other unique information needed for reports can generally be done by CRIC quickly and efficiently. Interactions with CRIC have been professional and newly generated reports have been done timely."

Kay Johnson
Associate Director for the Clinical Investigations Support Office
USC Clinical Trials Office

" As PI of an R34 pilot and planning grant from the National Institute of Dental and Craniofacial Research, we are using the CAFE system developed at USC’s Norris Comprehensive Cancer Institute. Our grant examines the efficacy of adapting the sensory characteristics of the dental office to enhance oral care for children with autism. At first, I had some hesitancy about using a program developed for cancer research however this program has been fully successful in meeting our needs. The team has done a fabulous job developing the data management system and has been extremely responsive to any “tweaking” needed. As we submit our U01, I will definitely continue to use CAFÉ... It has far exceeded my expectations. "


Sharon A. Cermak
Professor of Occupational Science and Occupational Therapy
University of Southern California

CAFE Logo


Testimonials

"I find CAFE overall the best compared to other databases I have used."
- Judy Villablanca, Associate Professor Clinical Pediatrics, Childrens Hospital Los Angeles, Medical Director, NANT

"I now always plan to incorporate the very reasonable costs of development of a CAFÉ database in my new grant submissions."
- Ann S. Hamilton, Ph.D.

"I can't speak highly enough of the skill and helpfulness of the Informatics Team at USC Norris. ...Informatics developed a customized version of CAFÉ that has proved to be a perfect fit for us in seminar event planning, tracking of program participants and more."
- Michelle Levander, Director, The California Endowment Health Journalism Fellowships

"Three years ago, the KSOM Research Advancement Office approached the Cancer Center Informatics Research Core (CRIC) about developing a grant awards and space occupation database for us to manage our $200M plus grant portfolio and KSOM’s 960,622 net square feet of space. (CRIC) worked closely with us to create a comprehensive database that is user friendly and invaluable in our day to day operations."
- Linda Mizushima, USC KSOM
- Janet A. Stoeckert, USC KSOM

"...Adding fields to café for capturing other unique information needed for reports can generally be done by CRIC quickly and efficiently."
- Kay Johnson

"I have found that just about any (CAFE) configuration is possible...(and) my staff members have found the databases easy to use."
- Ann S. Hamilton, Ph.D.

"The team has done a fabulous job developing the data management system and has been extremely responsive to any “tweaking” needed. As we submit our U01, I will definitely continue to use CAFÉ... It has far exceeded my expectations."
- Sharon A. Cermak
Professor of Occupational Science and Occupational Therapy
University of Southern California